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HIT214318752
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HIT214318752
  • HIT ID:HIT214318752
  • Cas No:74578-01-1
  • 常用名:Thaspine acetate
  • 别名:NSC-135784, NSC135784, NSC 135784
  • IUPAC:5-[2-(dimethylamino)ethyl]-7,14-dimethoxy-2,9-dioxatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(15),4,6,8(16),11,13-hexaene-3,10-dione; acetic acid
    IUPAC:5-[2-(dimethylamino)ethyl]-7,14-dimethoxy-2,9-dioxatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(15),4,6,8(16),11,13-hexaene-3,10-dione; acetic acid
  • InChI key:HUNGYFRUEMVMMI-UHFFFAOYSA-N
  • 分子式:C22H23NO8
  • 分子量:429.425
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CC(O)=O.COc1ccc2c3c1oc(=O)c1c(CCN(C)C)cc(OC)c(oc2=O)c31
    SMILES:CC(O)=O.COc1ccc2c3c1oc(=O)c1c(CCN(C)C)cc(OC)c(oc2=O)c31
  • Thaspine acetate is a potent topoisomerase IB inhibitor. Taspine downregulates VEGF expression and inhibits proliferation of vascular endothelial cells through PI3 kinase and MAP kinase signaling pathways.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    8-10周
    纯度
    -
    ¥ 12,800.00
    1

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