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  3. HIT214319566
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HIT214319566
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HIT214319566
  • HIT ID:HIT214319566
  • Cas No:62928-11-4
  • 常用名:Iproplatin
  • 别名:JM-9, JM 9, Code name: JM9, CHIP
  • IUPAC:
    IUPAC:
  • InChI key:LXOQJFIJHIXZQB-UHFFFAOYSA-L
  • 分子式:C6H16Cl2N2O2Pt
  • 分子量:414.19
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CC(C)[N][Pt+4]([OH-])([OH-])([Cl-])([Cl-])[N]C(C)C |^1:3,7,8,9|jcExt:v:5:2,6:2
    SMILES:CC(C)[N][Pt+4]([OH-])([OH-])([Cl-])([Cl-])[N]C(C)C |^1:3,7,8,9|jcExt:v:5:2,6:2
  • Iproplatin is a synthetic second-generation platinum-containing compound related to cisplatin. Iproplatin binds to and forms DNA crosslinks and platinum-DNA adducts, resulting in DNA replication failure and cell death. Although less prone to glutathione inactivation compared to cisplatin, resistance to this agent has been observed in vitro due to repair of platination damage by tumor cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 10,600.00
    1

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