Name: RTC14
Rating: 5 (10 reviews)

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sdf 文件

结构编辑

类似物检索

HIT ID:HIT214320175
Cas No:414909-09-4
常用名:RTC14
别名:RTC-14, RTC 14, Read-through compound-14, Read-through compound 14
别名:RTC-14, RTC 14, Read-through compound-14, Read-through compound 14
IUPAC:4-tert-butyl-2-{[(3-nitrophenyl)methylidene]amino}phenol
IUPAC:4-tert-butyl-2-{[(3-nitrophenyl)methylidene]amino}phenol
InChI key:SRROYBWFBCWHGV-UHFFFAOYSA-N

分子式:C17H18N2O3
分子量:298.342
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CC(C)(C)c1ccc(O)c(c1)N=Cc1cccc(c1)N(=O)=O |w:12.13|
SMILES:CC(C)(C)c1ccc(O)c(c1)N=Cc1cccc(c1)N(=O)=O |w:12.13|

RTC14, as a premature termination codon (PTC) readthrough inducer, can act by restoring dystrophin expression and improving muscle function in the mdx mouse model for Duchenne muscular dystrophy.

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