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HIT214320632
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HIT214320632
  • HIT ID:HIT214320632
  • Cas No:895127-66-9
  • 常用名:(±)7(8)-EpDPA
  • IUPAC:(4Z)-6-{3-[(2Z,5Z,8Z,11Z)-tetradeca-2,5,8,11-tetraen-1-yl]oxiran-2-yl}hex-4-enoic acid
    IUPAC:(4Z)-6-{3-[(2Z,5Z,8Z,11Z)-tetradeca-2,5,8,11-tetraen-1-yl]oxiran-2-yl}hex-4-enoic acid
  • InChI key:OHYKIJBTVXMLKX-MPQBXPHNSA-N
  • 分子式:C22H32O3
  • 分子量:344.495
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CC\C=C/C\C=C/C\C=C/C\C=C/CC1OC1C\C=C/CCC(O)=O
    SMILES:CC\C=C/C\C=C/C\C=C/C\C=C/CC1OC1C\C=C/CCC(O)=O
  • Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina. (±)7(8)-EpDPA is an epoxide derivative of DHA that is generated by the action of cytochrome P450 epoxygenases. It is naturally occurring in plasma and brain and spinal cord tissues and is increased following dietary supplementation with ω-3 fatty acids. (±)7(8)-EpDPA and other epoxy metabolites of DHA modulate receptor and channel activities to evoke diverse effects, such as promoting vasodilation, inhibiting angiogenesis, and decreasing inflammatory and neuropathic pain. (±)7(8)-EpDPA is a substrate of soluble epoxide hydrolase (KM = 15 μM), which converts it to the corresponding diol.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 987.00
    1

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