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- HIT ID:HIT214320701
- Cas No:691410-93-2
- 常用名:AN-7
- InChI key:QGUXZRFEKWOQQL-UHFFFAOYSA-N
- 分子式:C19H34N2O2S4
- 分子量:450.73
- 氢键供体数 (HBD):
- 氢键受体数 (HBA):
- LogP:
- α-Lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. It is an essential cofactor for decarboxylation reactions of the citric acid cycle and acts as a general antioxidant. AN-7 is a more lipophilic analog of α-lipoic acid with enhanced potency and 1.5-fold increased maximal capacity to stimulate glucose transport into myocytes. This identifies the analogs of lipoic acid as potential new treatments for diabetes.
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