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- HIT ID:HIT214320732
- Cas No:82005-44-5
- 常用名:Oleic Acid-13C
- InChI key:ZQPPMHVWECSIRJ-OLLJCFGNSA-N
- 分子式:C18H34O2
- 分子量:283.46
- 氢键供体数 (HBD):
- 氢键受体数 (HBA):
- LogP:
- Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been found in human plasma, cell membranes, and adipose tissue.1,2 It contributes approximately 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets.1 Oleic acid inhibits collagen-stimulated platelet aggregation by approximately 90% when used at a concentration of 10 μg/ml. It also inhibits fMLF-induced neutrophil aggregation and degranulation by 55 and 68%, respectively, when used at a concentration of 5 μM, similar to arachidonic acid .3 Oleic acid (60 μM) induces release of intracellular calcium in human platelets.4
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