Name: HC Toxin
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT214320771
Cas No:83209-65-8
常用名:HC Toxin
IUPAC:(3S,6R,9S,14aR)-3,6-dimethyl-9-{6-[(2S)-oxiran-2-yl]-6-oxohexyl}-tetradecahydropyrrolo[1,2-a]1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrone
IUPAC:(3S,6R,9S,14aR)-3,6-dimethyl-9-{6-[(2S)-oxiran-2-yl]-6-oxohexyl}-tetradecahydropyrrolo[1,2-a]1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrone
InChI key:GNYCTMYOHGBSBI-SVZOTFJBSA-N

分子式:C21H32N4O6
分子量:436.509
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[H][C@]12CCCN1C(=O)[C@H](CCCCCC(=O)[C@@H]1CO1)NC(=O)[C@@H](C)NC(=O)[C@H](C)NC2=O
SMILES:[H][C@]12CCCN1C(=O)[C@H](CCCCCC(=O)[C@@H]1CO1)NC(=O)[C@@H](C)NC(=O)[C@H](C)NC2=O

HC Toxin is a cell-permeable, reversible inhibitor of histone deacetylases (HDACs) (IC50 = 30 nM). Through its effects on HDACs, HC toxin has been shown to up-regulate the expression of 15-lipoxygenase-1 in colorectal cancer cells and induce fetal hemoglobin in human primary erythroid cells. HC Toxin is a cyclic tetrapeptide first isolated from H. carbonum (now C. carbonum), a pathogen of maize.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~