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  3. HIT214320817
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HIT214320817
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HIT214320817
  • HIT ID:HIT214320817
  • Cas No:115461-40-0
  • 常用名:19(S)-HETE
  • IUPAC:(5Z,8Z,11Z,14Z,19S)-19-hydroxyicosa-5,8,11,14-tetraenoic acid
    IUPAC:(5Z,8Z,11Z,14Z,19S)-19-hydroxyicosa-5,8,11,14-tetraenoic acid
  • InChI key:XFUXZHQUWPFWPR-DZBJBCEBSA-N
  • 分子式:C20H32O3
  • 分子量:320.473
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:C[C@H](O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
    SMILES:C[C@H](O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
  • 19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19(S)- and 19(R)-HETE are potent vasodilators of renal preglomerular vessels. 19(S)-HETE stimulates both renal sodium-potassium ATPase and volume absorption in the rabbit proximal straight tubule.
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  • 供应商
    TargetMolSC
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    货期
    35日内发货
    纯度
    -
    ¥ 3,690.00
    1

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