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  3. HIT214320862
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HIT214320862
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HIT214320862
  • HIT ID:HIT214320862
  • Cas No:119959-65-8
  • 常用名:N-Arachidonoyl Taurine
  • IUPAC:2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenamido]ethane-1-sulfonic acid
    IUPAC:2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenamido]ethane-1-sulfonic acid
  • InChI key:YUNYSWCRLRYOPO-DOFZRALJSA-N
  • 分子式:C22H37NO4S
  • 分子量:411.6
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCS(O)(=O)=O
    SMILES:CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCS(O)(=O)=O
  • N-Arachidonoyl taurine is an arachidonoyl amino acid. It is oxygenated by 12(S)- and 15(S)-lipoxygenase and is converted to 12-HETE-taurine (12-HETE-T) in murine resident peritoneal macrophages. N-Arachidonoyl taurine is an activator of the transient receptor potential vanilloid (TRPV) channels TRPV1 and TRPV4 (EC50s = 28 and 21 μM, respectively). It increases calcium flux in HIT-T15 pancreatic β-cells and INS-1 rat islet cells when used at a concentration of 10 μM and increases insulin secretion from 832/13 INS-1 pancreatic β-cells. The levels of N-arachidonoyl taurine are changed in mouse brain following administration of δ9-tetrahydrocannabinol (δ9-THC).
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  • 供应商
    TargetMolSC
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    货期
    35日内发货
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    -
    ¥ 1,980.00
    1

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