Name: D-myo-Inositol-4-phosphate (ammonium salt)
Rating: 5 (10 reviews)

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HIT ID:HIT214320876
Cas No:142760-33-6
常用名:D-myo-Inositol-4-phosphate (ammonium salt)
常用名:D-myo-Inositol-4-phosphate (ammonium salt)
IUPAC:{[(1S,2R,3S,4S,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphonic acid amine
IUPAC:{[(1S,2R,3S,4S,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphonic acid amine
InChI key:REMBBOONLXQKLK-SUBVTSALSA-N

分子式:C6H16NO9P
分子量:277.166
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:N.O[C@@H]1[C@H](O)[C@H](O)[C@@H](OP(O)(O)=O)[C@H](O)[C@H]1O
SMILES:N.O[C@@H]1[C@H](O)[C@H](O)[C@@H](OP(O)(O)=O)[C@H](O)[C@H]1O

D-myo-Inositol-4-phosphate (Ins(4)P1) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-diphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(4)P1 can be formed by dephosphorylation of Ins(1,4)P2 by inositol polyphosphate 1-phosphatase or dephosphorylated to inositol by inositol monophosphatase.

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