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  3. HIT214320900
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HIT214320900
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HIT214320900
  • HIT ID:HIT214320900
  • Cas No:139141-12-1
  • 常用名:CAY10512
  • IUPAC:1-[(1E)-2-(2-fluorophenyl)ethenyl]-4-methoxybenzene
    IUPAC:1-[(1E)-2-(2-fluorophenyl)ethenyl]-4-methoxybenzene
  • InChI key:ILVFNAZMSMNXJG-RMKNXTFCSA-N
  • 分子式:C15H13FO
  • 分子量:228.266
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:COc1ccc(\C=C\c2ccccc2F)cc1
    SMILES:COc1ccc(\C=C\c2ccccc2F)cc1
  • The nuclear factor-κB (NF-κB) regulates the expression of numerous genes involved in immunity and inflammation, cellular stress responses, growth, and apoptosis. Resveratrol, a polyphenolic trans-stilbene, is a known inhibitor of the activation of NF-κB and exhibits activity against a wide variety of cancer cells. CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activation of NF-κB by CAY10512 is 0.15 μM compared to 20 μM by resveratrol.
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  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 1,130.00
    1

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