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HIT214320995
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HIT214320995
  • HIT ID:HIT214320995
  • Cas No:519038-92-7
  • 常用名:14,15-EE-5(Z)-E
  • IUPAC:(5Z)-13-[(2R,3S)-3-pentyloxiran-2-yl]tridec-5-enoic acid
    IUPAC:(5Z)-13-[(2R,3S)-3-pentyloxiran-2-yl]tridec-5-enoic acid
  • InChI key:KZTLOTWHEAHQAZ-CUZNAYPQSA-N
  • 分子式:C20H36O3
  • 分子量:324.505
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CCCCC[C@@H]1O[C@@H]1CCCCCCC\C=C/CCCC(O)=O
    SMILES:CCCCC[C@@H]1O[C@@H]1CCCCCCC\C=C/CCCC(O)=O
  • Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity. 14,15-EE-5(Z)-E is a structural analog of 14,15-epoxyeicosatrienoic acids (14,15-EET) that antagonizes EET-induced relaxation of vascular smooth muscle. Relaxation of U46619-constricted bovine arteries by 14,15-EET could be inhibited approximately 80% by 14,15-EE-5(Z)-E at a concentration of 10 μM. 14,15-EE-5(Z)-E does not appear to antagonize nitric oxide- or iloprost-mediated vascular relaxation.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 1,080.00
    1

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