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  3. HIT214321033
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HIT214321033
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HIT214321033
  • HIT ID:HIT214321033
  • Cas No:196493-76-2
  • 常用名:2,3-dinor Thromboxane B1
  • 别名:2,3-dinor Thromboxane B1
  • IUPAC:5-[(2R,3S,4S)-4,6-dihydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]oxan-3-yl]pentanoic acid
    IUPAC:5-[(2R,3S,4S)-4,6-dihydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]oxan-3-yl]pentanoic acid
  • InChI key:LGWCOUWMTAQMQT-QCBHMXSDSA-N
  • 分子式:C18H32O6
  • 分子量:344.448
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CCCCC[C@H](O)\C=C\[C@H]1OC(O)C[C@H](O)[C@@H]1CCCCC(O)=O
    SMILES:CCCCC[C@H](O)\C=C\[C@H]1OC(O)C[C@H](O)[C@@H]1CCCCC(O)=O
  • Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2. In rats and rabbits, 2,3-dinor TXB1 has been identified as another urinary metabolite of TXB2. However in human urine, only trace amounts of 2,3-dinor TXB1 have been identified. In rats, 2,3-dinor TXB1 is excreted at a much higher rate than 2,3-dinor TXB2 (19.2 ± 4.9 ng/24 hr and 1.6 ± 0.3 ng/24 hr, respectively). Therefore, urinary 2,3-dinor TXB1 is a suitable marker of thromboxane biosynthesis in rats.
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  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
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    -
    ¥ 2,870.00
    1

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