Name: N-p-Tosyl-Gly-Pro-Lys-pNA (acetate)
Rating: 5 (10 reviews)

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结构编辑

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HIT ID:HIT214321034
Cas No:88793-79-7
常用名:N-p-Tosyl-Gly-Pro-Lys-pNA (acetate)
常用名:N-p-Tosyl-Gly-Pro-Lys-pNA (acetate)
IUPAC:(2S)-6-amino-2-{[(2S)-1-[2-(4-methylbenzenesulfonamido)acetyl]pyrrolidin-2-yl]formamido}-N-(4-nitrophenyl)hexanamide; acetic acid
IUPAC:(2S)-6-amino-2-{[(2S)-1-[2-(4-methylbenzenesulfonamido)acetyl]pyrrolidin-2-yl]formamido}-N-(4-nitrophenyl)hexanamide; acetic acid
InChI key:KPGSNEYSJPIZCW-SJEIDVEUSA-N

分子式:C28H38N6O9S
分子量:634.71
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CC(O)=O.Cc1ccc(cc1)S(=O)(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)Nc1ccc(cc1)N(=O)=O
SMILES:CC(O)=O.Cc1ccc(cc1)S(=O)(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)Nc1ccc(cc1)N(=O)=O

N-p-Tosyl-Gly-Pro-Lys-pNA is a colorimetric substrate for plasmin.1,2,3Plasmin binds and hydrolyzes N-p-tosyl-Gly-Pro-Lys-pNA to releasep-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of plasmin activity.

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