Name: Protease-Activated Receptor-3 (PAR-3) (1-6), human
Rating: 5 (10 reviews)

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HIT ID:HIT214321061
Cas No:1872435-09-0
常用名:Protease-Activated Receptor-3 (PAR-3) (1-6), human
常用名:Protease-Activated Receptor-3 (PAR-3) (1-6), human
IUPAC:(2S)-1-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-phenylpropanamido]-5-carbamimidamidopentanamido]acetamido}propanoyl]pyrrolidine-2-carboxamide
IUPAC:(2S)-1-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-phenylpropanamido]-5-carbamimidamidopentanamido]acetamido}propanoyl]pyrrolidine-2-carboxamide
InChI key:SZHZUHWALRYMHX-WZZXNIEWSA-N

分子式:C29H46N10O7
分子量:646.75
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:C[C@@H](O)[C@H](N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(N)=O
SMILES:C[C@@H](O)[C@H](N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(N)=O

TFRGAP-amide, human PAR-3-derived tethered ligand sequence which does not activate PAR-3 but rather activates PAR-1 and PAR-2, either in Jurkat or in other PAR-expressing cells.

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