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HIT214321141
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HIT214321141
  • HIT ID:HIT214321141
  • Cas No:1807365-35-0
  • 常用名:Contezolid acefosamil sodium
  • IUPAC:(acetyloxy)[(1,2-oxazol-3-yl)({[(5R)-2-oxo-3-[2,3,5-trifluoro-4-(4-oxo-1,2,3,4-tetrahydropyridin-1-yl)phenyl]-1,3-oxazolidin-5-yl]methyl})amino]phosphinic acid sodium
    IUPAC:(acetyloxy)[(1,2-oxazol-3-yl)({[(5R)-2-oxo-3-[2,3,5-trifluoro-4-(4-oxo-1,2,3,4-tetrahydropyridin-1-yl)phenyl]-1,3-oxazolidin-5-yl]methyl})amino]phosphinic acid sodium
  • InChI key:JBOXVHQQSOBQAA-BTQNPOSSSA-N
  • 分子式:C20H18F3N4NaO8P
  • 分子量:553.343
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:[Na].CC(=O)OP(O)(=O)N(C[C@H]1CN(C(=O)O1)c1cc(F)c(N2CCC(=O)C=C2)c(F)c1F)c1ccon1 |c:26|
    SMILES:[Na].CC(=O)OP(O)(=O)N(C[C@H]1CN(C(=O)O1)c1cc(F)c(N2CCC(=O)C=C2)c(F)c1F)c1ccon1 |c:26|
  • Contezolid acefosamil sodium (MRX-4) is a novel orally active oxazolidinone antibiotic under investigation for the treatment of complicated skin and soft tissue infections (cSSTI) caused by drug-resistant Gram-positive bacteria. It possesses strong efficacy against these pathogens while significantly minimizing the risks of myelosuppression and monoamine oxidase inhibition (MAOI) [1][2].
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  • 供应商
    TargetMolSC
    规格
    货期
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    -
    ¥ 7,419.00
    1

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