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  3. HIT214321311
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HIT214321311
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HIT214321311
  • HIT ID:HIT214321311
  • Cas No:52977-29-4
  • 常用名:1-Octadecyl Lysophosphatidic Acid
    常用名:1-Octadecyl Lysophosphatidic Acid
  • IUPAC:[2-hydroxy-3-(octadecyloxy)propoxy]phosphonic acid
    IUPAC:[2-hydroxy-3-(octadecyloxy)propoxy]phosphonic acid
  • InChI key:HUUYDUFSUADEJQ-UHFFFAOYSA-N
  • 分子式:C21H45O6P
  • 分子量:424.559
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CCCCCCCCCCCCCCCCCCOCC(O)COP(O)(O)=O
    SMILES:CCCCCCCCCCCCCCCCCCOCC(O)COP(O)(O)=O
  • 1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has a platelet aggregating EC50 value of 9 nM versus 1-octadecanoyl LPA which has an EC50 value of 177 nM.
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    TargetMolSC
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    35日内发货
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    ¥ 1,230.00
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