Name: 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT214321335
Cas No:61263-35-2
常用名:9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
常用名:9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
别名:9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
别名:9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
IUPAC:(5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4,4-dimethyloct-1-en-1-yl]-5-methylidenecyclopentyl]hept-5-enoic acid
IUPAC:(5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4,4-dimethyloct-1-en-1-yl]-5-methylidenecyclopentyl]hept-5-enoic acid
InChI key:WMLGLMGSFIXSGO-KTXJXPLISA-N

分子式:C23H38O4
分子量:378.553
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CCCCC(C)(C)[C@H](O)\C=C\[C@H]1[C@H](O)CC(=C)[C@@H]1C\C=C/CCCC(O)=O
SMILES:CCCCC(C)(C)[C@H](O)\C=C\[C@H]1[C@H](O)CC(=C)[C@@H]1C\C=C/CCCC(O)=O

9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 with an extended half-life in vivo. In combination with various other prostaglandin derivatives, it results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of meteneprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy. This prostaglandin mixture is ineffective on monkeys in their third trimester of pregnancy. Meteneprost, when compared to PGE2 and PGF1α, in monkey and rat, does not result in unwanted side effects such as fever or gastrointestinal problems.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~