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- HIT ID:HIT214321391
- Cas No:433212-75-0
- 常用名:SSAA09E1
- 别名:SSAA09E1
- InChI key:PJVHAJJEMJNPHN-UITAMQMPSA-N
- 分子式:C7H9N3S2
- 分子量:199.29
- 氢键供体数 (HBD):
- 氢键受体数 (HBA):
- LogP:
- SSAA09E1 is an inhibitor of severe acute respiratory syndrome coronavirus (SARS-CoV) viral entry.1It reduces infection of HEK293T cells transiently transfected with angiotensin-converting enzyme 2 (ACE2) by an HIV-based virus system pseudotyped with SARS-CoV surface glycoprotein (EC50= 6.7 μM). SSAA09E1 also inhibits the proteolytic activity of cathepsin L (IC50= 5.33 μM) but not cathepsin B when used at a concentration of 20 μM.
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