Name: Previridicatumtoxin
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT214321424
Cas No:1379585-81-5
常用名:Previridicatumtoxin
IUPAC:(4aS,5S,12aS)-6-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3,4a,5,10,11,12a-hexahydroxy-8-methoxy-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide
IUPAC:(4aS,5S,12aS)-6-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3,4a,5,10,11,12a-hexahydroxy-8-methoxy-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide
InChI key:KQHILJSZLCTZEG-BJTDMJNKSA-N

分子式:C30H33NO10
分子量:567.591
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[#6]-[#8]-c1cc(-[#8])c2c(-[#8])c3-[#6](=O)[C@]4([#8])[#6](=O)-[#6](-[#6](-[#7])=O)=[#6](-[#8])-[#6][C@]4([#8])[#6@@H](-[#8])-c3c(-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])c2c1 |t:19|
SMILES:[#6]-[#8]-c1cc(-[#8])c2c(-[#8])c3-[#6](=O)[C@]4([#8])[#6](=O)-[#6](-[#6](-[#7])=O)=[#6](-[#8])-[#6][C@]4([#8])[#6@@H](-[#8])-c3c(-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])c2c1 |t:19|

Previridicatumtoxin is a fungal metabolite that has been found inP. aethiopicumand has diverse biological activities.1,2It is an intermediate in the biosynthesis of the mycotoxin viridicatumtoxin . Previridicatumtoxin is active against methicillin-resistantS. aureus(MRSA) and vancomycin-resistantE. faecalis(IC50s = 4.4 and 4.8 μM, respectively), as well asC. albicansandS. cerevisiae(MIC = 32 μg/ml for both).2,1It is cytotoxic to NCI H460, KB-3-1, and SW620 cancer cells (IC50s = 5.3, 4.1, and 6 μM, respectively).2

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~