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  3. HIT214321679
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HIT214321679
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HIT214321679
  • HIT ID:HIT214321679
  • Cas No:1649473-91-5
  • 常用名:CAY10742
  • IUPAC:5-{3-[4-(4-fluorophenoxy)phenyl]-1,2,4-oxadiazol-5-yl}-1H-indole
    IUPAC:5-{3-[4-(4-fluorophenoxy)phenyl]-1,2,4-oxadiazol-5-yl}-1H-indole
  • InChI key:LJMUZZUGHRTIJT-UHFFFAOYSA-N
  • 分子式:C22H14FN3O2
  • 分子量:371.371
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:Fc1ccc(Oc2ccc(cc2)-c2noc(n2)-c2ccc3[nH]ccc3c2)cc1
    SMILES:Fc1ccc(Oc2ccc(cc2)-c2noc(n2)-c2ccc3[nH]ccc3c2)cc1
  • CAY10742 is an orally bioavailable oxadiazole antibiotic.1It is active against the Gram-positive bacteriaS. aureus,S. epidermidis,S. haemolyticus,B. cereus,B. licheniformis,E. faecalis, andE. faecium(MICs = 1-4 μg/ml), including laboratory strains and clinical isolates with varying degrees of resistance to methicillin, vancomycin, linezolid, and other antibiotics. CAY10742 (40 mg/kg) reduces the number of bacteria in mouse neutropenic thigh models of linezolid-sensitive or -resistant methicillin-resistantS. aureus(MRSA) infection.
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  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 1,080.00
    1

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