Name: GW 1929 hydrochloride
Rating: 5 (10 reviews)

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HIT ID:HIT214321744
Cas No:1217466-21-1
常用名:GW 1929 hydrochloride
IUPAC:(2S)-2-[(2-benzoylphenyl)amino]-3-(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)propanoic acid hydrochloride
IUPAC:(2S)-2-[(2-benzoylphenyl)amino]-3-(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)propanoic acid hydrochloride
InChI key:KXNKIKXTGRMLEY-YCBFMBTMSA-N

分子式:C30H30ClN3O4
分子量:532.04
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:Cl.CN(CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(O)=O)cc1)c1ccccn1
SMILES:Cl.CN(CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(O)=O)cc1)c1ccccn1

Highly selective orally active peroxisome proliferator-activated receptor (PPAR)γ agonist (pEC50 values are 8.05, < 4 and < 4 for human PPARγ, PPARα and PPARδ receptors respectively). Decreases glucose, fatty acid and triglyceride levels following oral administration in vivo.

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