Name: Leukotriene B4 dimethyl amide
Rating: 5 (10 reviews)

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HIT ID:HIT214321763
Cas No:83024-92-4
常用名:Leukotriene B4 dimethyl amide
别名:Leukotriene B4 dimethyl amide
IUPAC:(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxy-N,N-dimethylicosa-6,8,10,14-tetraenamide
IUPAC:(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxy-N,N-dimethylicosa-6,8,10,14-tetraenamide
InChI key:BBJRTSLPWQUASB-UKODYPNASA-N

分子式:C22H37NO3
分子量:363.542
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CCCCC\C=C/C[C@@H](O)\C=C\C=C\C=C/[C@@H](O)CCCC(=O)N(C)C
SMILES:CCCCC\C=C/C[C@@H](O)\C=C\C=C\C=C/[C@@H](O)CCCC(=O)N(C)C

LTB4 dimethyl amide is a moderate inhibitor of LTB4-induced degranulation of human neutrophils (Ki = 130 nM) and lysozyme release from rat PMNL. LTB4 dimethyl amide appears to be an antagonist of the LTB4 receptor on guinea pig lung membranes.

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