购物车
0
有库存
sdf 文件
结构编辑
类似物检索
- HIT ID:HIT214321768
- Cas No:121842-79-3
- 常用名:tetranor-12(S)-HETE
- InChI key:KBOVKDIBOBQLRS-ONCCEEIJSA-N
- 分子式:C16H26O3
- 分子量:266.381
- 氢键供体数 (HBD):
- 氢键受体数 (HBA):
- LogP:
- 12(S)-HETE is a product of arachidonic acid metabolism through the 12-lipoxygenase pathway. It is primarily found in platelets, leukocytes, and to a lesser extent in smooth muscle cells. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix. tetranor-12(S)-HETE is the major β-oxidation product resulting from peroxisomal metabolism of 12(S)-HETE in numerous tissues, and Lewis lung carcinoma cells. No biological function has yet been determined for tetranor-12(S)-HETE. Some data indicate it may play a role in controlling the inflammatory response in injured corneas. In some diseases (e.g., Zellweger's Syndrome) peroxisomal abnormalities result in the inability of cells to metabolize 12(S)-HETE, which may be responsible for symptoms of the disease. The tetranor derivative of 12(S)-HETE is available as a research tool for the elucidation of the metabolic fate of its parent compound.
市场产品/服务共显示1个结果
- 供应商TargetMol规格货期35日内发货纯度-¥ 3,970.001
寻找合适的化合物库
您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。
电话：400820-0310
合作：info@screeningcompound.com
技术支持：tech@screeningcompound.com
客服：service@screeningcompound.com
查看大图
正在加载 ~