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HIT214321832
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HIT214321832
  • HIT ID:HIT214321832
  • Cas No:1675245-06-3
  • 常用名:N-cis-tetradec-9Z-enoyl-L-Homoserine lactone
    常用名:N-cis-tetradec-9Z-enoyl-L-Homoserine lactone
  • IUPAC:(9Z)-N-[(3S)-2-oxooxolan-3-yl]tetradec-9-enamide
    IUPAC:(9Z)-N-[(3S)-2-oxooxolan-3-yl]tetradec-9-enamide
  • InChI key:CNVCBUGVTPVVJB-KJPDOMRESA-N
  • 分子式:C18H31NO3
  • 分子量:309.45
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CCCC\C=C/CCCCCCCC(=O)N[C@H]1CCOC1=O
    SMILES:CCCC\C=C/CCCCCCCC(=O)N[C@H]1CCOC1=O
  • Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group) and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family. C14:1-δ9-cis-(L)-HSL is a long-chain AHL that functions as a signaling molecule in the quorum sensing of A. vitis. Regulating bacterial quorum sensing signaling can be used to inhibit pathogenesis and thus, represents a new approach to antimicrobial therpy in the treatment of infectious diseases.
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  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 1,190.00
    1

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