Name: PF 04671536 hydrochloride
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT214321856
Cas No:1305116-67-9
常用名:PF 04671536 hydrochloride
IUPAC:5-methyl-3-{[(2R)-4-[(1,3-thiazol-2-yl)methyl]morpholin-2-yl]methyl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine hydrochloride
IUPAC:5-methyl-3-{[(2R)-4-[(1,3-thiazol-2-yl)methyl]morpholin-2-yl]methyl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine hydrochloride
InChI key:KNBIGIZPAKPDTF-HNCPQSOCSA-N

分子式:C14H19ClN8OS
分子量:382.87
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:Cl.Cc1nc(N)c2nnn(C[C@H]3CN(Cc4nccs4)CCO3)c2n1
SMILES:Cl.Cc1nc(N)c2nnn(C[C@H]3CN(Cc4nccs4)CCO3)c2n1

Potent and selective PDE8B/8A inhibitor ( IC50 values are 1.3 and 1.9 nM, respectively). Exhibits selectivity for PDE8A/B over other PDEs (IC50 values are >10 μM) and a range of other targets. Increases glucose-dependent insulin secretion from human pacreatic islet cells. Orally bioavailable.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~