BHBM | CAS 302807-84-7 | AnyMole

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HIT214321909

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HIT214321909

HIT ID:HIT214321909
Cas No:302807-84-7
常用名:BHBM
IUPAC:N'-[(5-bromo-2-hydroxyphenyl)methylidene]-2-methylbenzohydrazide
IUPAC:N'-[(5-bromo-2-hydroxyphenyl)methylidene]-2-methylbenzohydrazide
InChI key:ZREZUYGIIHJUAR-UHFFFAOYSA-N

分子式:C15H13BrN2O2
分子量:333.185
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:Cc1ccccc1C(=O)NN=Cc1cc(Br)ccc1O |w:10.10|
SMILES:Cc1ccccc1C(=O)NN=Cc1cc(Br)ccc1O |w:10.10|

BHBM is an acylhydrazone with antifungal activity.1,2 It is active against C. neoformans in vitro (MIC80 = 1 μg/ml).2 BHBM (0.25, 1, and 4 μg/ml) inhibits the synthesis of glucosylceramide, which is essential to fungal cell division, in C. neoformans but not J774 murine macrophages.1

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