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  3. HIT214321930
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HIT214321930
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HIT214321930
  • HIT ID:HIT214321930
  • Cas No:51638-90-5
  • 常用名:16-phenoxy tetranor Prostaglandin F2α methyl ester
    常用名:16-phenoxy tetranor Prostaglandin F2α methyl ester
  • 别名:16-phenoxy tetranor Prostaglandin F2α methyl ester
    别名:16-phenoxy tetranor Prostaglandin F2α methyl ester
  • IUPAC:methyl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxybut-1-en-1-yl]cyclopentyl]hept-5-enoate
    IUPAC:methyl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxybut-1-en-1-yl]cyclopentyl]hept-5-enoate
  • InChI key:HYOHKXGCEWCBKE-CNAXQHPCSA-N
  • 分子式:C23H32O6
  • 分子量:404.503
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:COC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COc1ccccc1
    SMILES:COC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COc1ccccc1
  • Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α (16-phenoxy tetranor PGF2α) is a metabolically stable form of PGF2α containing a 16-phenoxy group at the ω-terminus. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α. 16-phenoxy tetranor PGF2α methyl ester is a lipophilic analog of 16-phenoxy tetranor PGF2α. Methyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
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  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 2,650.00
    1

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