Name: 17-phenoxy trinor Prostaglandin F2α ethyl amide
Rating: 5 (10 reviews)

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HIT ID:HIT214321931
Cas No:1421369-12-1
常用名:17-phenoxy trinor Prostaglandin F2α ethyl amide
常用名:17-phenoxy trinor Prostaglandin F2α ethyl amide
别名:17-phenoxy trinor Prostaglandin F2α ethyl amide
别名:17-phenoxy trinor Prostaglandin F2α ethyl amide
IUPAC:(5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenoxypent-1-en-1-yl]cyclopentyl]-N-ethylhept-5-enamide
IUPAC:(5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenoxypent-1-en-1-yl]cyclopentyl]-N-ethylhept-5-enamide
InChI key:QGDXYIFHBPXXOY-HQUSFCFYSA-N

分子式:C25H37NO5
分子量:431.573
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CCNC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCOc1ccccc1
SMILES:CCNC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCOc1ccccc1

Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. Both 17-phenyl trinor PGF2α and 16-phenoxy tetranor PGF2α are metabolically stable analogs of PGF2α and potent agonists for the FP receptor. 17-phenoxy trinor PGF2α ethyl amide is a lipophilic analog of 17-phenoxy trinor PGF2α . Ethyl amides of PGs serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.

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