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HIT214322046
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HIT214322046
  • HIT ID:HIT214322046
  • Cas No:540-12-5
  • 常用名:Ricinelaidic Acid
  • IUPAC:(9E,12R)-12-hydroxyoctadec-9-enoic acid
    IUPAC:(9E,12R)-12-hydroxyoctadec-9-enoic acid
  • InChI key:WBHHMMIMDMUBKC-XLNAKTSKSA-N
  • 分子式:C18H34O3
  • 分子量:298.467
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CCCCCC[C@@H](O)C\C=C\CCCCCCCC(O)=O
    SMILES:CCCCCC[C@@H](O)C\C=C\CCCCCCCC(O)=O
  • Ricinelaidic acid is a 12-hydroxy fatty acid and an antagonist of leukotriene B4 (LTB4) receptors (Ki = 2 μM in porcine neutrophil membranes). It inhibits chemotaxis and calcium flux induced by LTB4 in isolated human neutrophils (IC50s = 10 and 7 μM, respectively). Ricinelaidic acid (1 mg/kg, i.v.) inhibits bronchoconstriction induced by LTB4 in rats by 46%.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 5,480.00
    1

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