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  3. HIT214322070
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HIT214322070
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HIT214322070
  • HIT ID:HIT214322070
  • Cas No:114200-59-8
  • 常用名:1-β-D-Glucosylsphingadienine (d18:2 (4E,8E))
    常用名:1-β-D-Glucosylsphingadienine (d18:2 (4E,8E))
  • 别名:1-β-D-Glucosylsphingadienine (d18:2 (4E,8E))
    别名:1-β-D-Glucosylsphingadienine (d18:2 (4E,8E))
  • IUPAC:2-[(2-amino-3-hydroxyoctadeca-4,8-dien-1-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
    IUPAC:2-[(2-amino-3-hydroxyoctadeca-4,8-dien-1-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
  • InChI key:HWRVJNPAUIAOKZ-UHFFFAOYSA-N
  • 分子式:C24H45NO7
  • 分子量:459.624
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CCCCCCCCCC=CCCC=CC(O)C(N)COC1OC(CO)C(O)C(O)C1O |w:14.14,10.10|
    SMILES:CCCCCCCCCC=CCCC=CC(O)C(N)COC1OC(CO)C(O)C(O)C1O |w:14.14,10.10|
  • 1-β-D-Glucosylsphingadienine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucosylcerebrosides . They are formed when sphingosines undergo glucosidation by UDP-glucose. Glucosylsphingosines completely reduce neurite outgrowth and induce death of LA-N-2 cells at concentrations of 10 and 50 μM, respectively. They also decrease the activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner. Glucosylsphingosine levels are elevated in patients with Gaucher's disease, both in the spleen (in types 1, 2, and 3) and brain (type 2 and 3); thus, glucosylsphingosine has been used as a key biomarker of the disease. This product contains 1-β-D-glucosylsphingadienine isolated from plants.
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  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 2,870.00
    1

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