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  3. HIT214322090
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HIT214322090
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HIT214322090
  • HIT ID:HIT214322090
  • Cas No:17094-01-8
  • 常用名:L-Sepiapterin
  • IUPAC:2-amino-6-[(2S)-2-hydroxypropanoyl]-1,4,7,8-tetrahydropteridin-4-one
    IUPAC:2-amino-6-[(2S)-2-hydroxypropanoyl]-1,4,7,8-tetrahydropteridin-4-one
  • InChI key:VPVOXUSPXFPWBN-VKHMYHEASA-N
  • 分子式:C9H11N5O3
  • 分子量:237.219
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:C[C@H](O)C(=O)C1=Nc2c(NC1)[nH]c(N)nc2=O |t:5|
    SMILES:C[C@H](O)C(=O)C1=Nc2c(NC1)[nH]c(N)nc2=O |t:5|
  • L-Sepiapterin, also known as Sepiapterin, is a precursor compound crucial for the production of tetrahydrobiopterin (BH4), which serves as a coenzyme for endothelial nitric oxide synthase (eNOS). This compound demonstrates its efficacy by improving endothelial dysfunction in small mesenteric arteries from db/db mice and promoting angiogenesis. Moreover, L-Sepiapterin exerts inhibitory effects on cellular proliferation and migration in ovarian cancer cells through the down-regulation of p70S6K-dependent vascular endothelial growth factor receptor-2 (VEGFR-2) expression[1][2].
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  • 供应商
    TargetMolSC
    规格
    货期
    1-3天
    纯度
    -
    ¥ 34,600.00
    1

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