Name: 93-O17S
Rating: 5 (10 reviews)

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HIT ID:HIT214322129
Cas No:2227008-67-3
常用名:93-O17S
别名:93-O17S
IUPAC:2-(tetradecylsulfanyl)ethyl 3-{[3-(1H-imidazol-1-yl)propyl]({3-oxo-3-[2-(tetradecylsulfanyl)ethoxy]propyl})amino}propanoate
IUPAC:2-(tetradecylsulfanyl)ethyl 3-{[3-(1H-imidazol-1-yl)propyl]({3-oxo-3-[2-(tetradecylsulfanyl)ethoxy]propyl})amino}propanoate
InChI key:OLOIOPYNTGMAAP-UHFFFAOYSA-N

分子式:C44H83N3O4S2
分子量:782.29
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CCCCCCCCCCCCCCSCCOC(=O)CCN(CCCn1ccnc1)CCC(=O)OCCSCCCCCCCCCCCCCC
SMILES:CCCCCCCCCCCCCCSCCOC(=O)CCN(CCCn1ccnc1)CCC(=O)OCCSCCCCCCCCCCCCCC

93-O17S is a chalcogen-containing cationic lipidoid.1It has been used in the synthesis of lipid nanoparticles (LPNs) for the delivery of Cre recombinase and ribonucleoproteins for genome editing in mice. LPNs containing 93-O17S have been used for the intratumoral delivery of cGAMP to enhance cross-presentation of tumor antigens and stimulation of interferon genes (STING) activation in a B16/F10 murine melanoma model.2

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