Name: JAMI1001A
Rating: 5 (10 reviews)

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sdf 文件

结构编辑

类似物检索

HIT ID:HIT214322167
Cas No:1001019-46-0
常用名:JAMI1001A
IUPAC:2-{2-[4-(hydroxymethyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetamido}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
IUPAC:2-{2-[4-(hydroxymethyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetamido}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
InChI key:ZGRBZBGNPZBNLW-UHFFFAOYSA-N

分子式:C16H17F3N4O3S
分子量:402.39
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:NC(=O)c1c2CCCCc2sc1NC(=O)Cn1cc(CO)c(n1)C(F)(F)F
SMILES:NC(=O)c1c2CCCCc2sc1NC(=O)Cn1cc(CO)c(n1)C(F)(F)F

JAMI1001A is a positive allosteric modulator of the AMPA receptor, effectively modulating the deactivation and desensitization of both flip and flop receptor isoforms.

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