Name: Propargyl-C8-amido-PEG2-NHS ester
Rating: 5 (10 reviews)

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HIT ID:HIT214322173
Cas No:1006592-59-1
常用名:Propargyl-C8-amido-PEG2-NHS ester
常用名:Propargyl-C8-amido-PEG2-NHS ester
别名:Propargyl-C8-amido-PEG2-NHS ester
IUPAC:2,5-dioxopyrrolidin-1-yl 3-{2-[2-(undec-10-ynamido)ethoxy]ethoxy}propanoate
IUPAC:2,5-dioxopyrrolidin-1-yl 3-{2-[2-(undec-10-ynamido)ethoxy]ethoxy}propanoate
InChI key:OMCLMLMPUVUIQP-UHFFFAOYSA-N

分子式:C22H34N2O7
分子量:438.521
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:O=C(CCCCCCCCC#C)NCCOCCOCCC(=O)ON1C(=O)CCC1=O
SMILES:O=C(CCCCCCCCC#C)NCCOCCOCCC(=O)ON1C(=O)CCC1=O

Propargyl-C8-amido-PEG2-NHS ester is a non-cleavable linker composed of two PEG units, primarily employed for the synthesis of antibody-drug conjugates (ADCs). This compound serves as an essential constituent that facilitates the conjugation of antibodies to drugs, enabling the targeted delivery of therapeutic agents.

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