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  3. HIT214322209
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HIT214322209
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HIT214322209
  • HIT ID:HIT214322209
  • Cas No:1050477-27-4
  • 常用名:(Rac)-Finerenone
  • 别名:(Rac)-Finerenone, (Rac)-BAY 94-8862
  • IUPAC:4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide
    IUPAC:4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide
  • InChI key:BTBHLEZXCOBLCY-UHFFFAOYSA-N
  • 分子式:C21H22N4O3
  • 分子量:378.432
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CCOc1ncc(C)c2NC(C)=C(C(c3ccc(cc3OC)C#N)c12)C(N)=O |c:11|
    SMILES:CCOc1ncc(C)c2NC(C)=C(C(c3ccc(cc3OC)C#N)c12)C(N)=O |c:11|
  • Rac-Finerenone, also known as (Rac)-BAY 94-8862, is the racemate derivative of Finerenone, a selective third-generation nonsteroidal mineralocorticoid receptor antagonist (MR) that is taken orally. With an IC50 value of 18 nM, Finerenone exhibits exceptional selectivity against the glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold).
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 7,420.00
    1

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