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  3. HIT214322370
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HIT214322370
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HIT214322370
  • HIT ID:HIT214322370
  • Cas No:1269190-98-8
  • 常用名:yGsy2p-IN-H23
  • 别名:yGsy2p-IN-H23
  • IUPAC:2-methoxy-4-{1-[2-(1-methylpyrrolidin-2-yl)ethyl]-4-phenyl-1H-imidazol-5-yl}phenol
    IUPAC:2-methoxy-4-{1-[2-(1-methylpyrrolidin-2-yl)ethyl]-4-phenyl-1H-imidazol-5-yl}phenol
  • InChI key:YGPHAIXUDLLWHC-UHFFFAOYSA-N
  • 分子式:C23H27N3O2
  • 分子量:377.488
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:COc1cc(ccc1O)-c1c(ncn1CCC1CCCN1C)-c1ccccc1
    SMILES:COc1cc(ccc1O)-c1c(ncn1CCC1CCCN1C)-c1ccccc1
  • yGsy2p-IN-H23 is a potent, first-in-class inhibitor specifically designed to target yeast glycogen synthase 2 (yGsy2p). It demonstrates an IC50 value of 875 μM for human glycogen synthase 1 (hGYS1). This compound binds precisely within the uridine diphosphate glucose (UDPG) binding pocket of yGsy2p. Its utilization in research primarily focuses on studying glycogen storage diseases (GSDs).
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  • 供应商
    TargetMolSC
    规格
    货期
    5日内发货
    纯度
    -
    ¥ 984.00
    1

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