Name: GSK2332255B
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT214322446
Cas No:1366233-41-1
常用名:GSK2332255B
IUPAC:5-chloro-4-(2,3-dimethylpiperidine-1-carbonyl)-N-(6-fluoro-2H-1,3-benzodioxol-5-yl)-1,3-thiazol-2-amine
IUPAC:5-chloro-4-(2,3-dimethylpiperidine-1-carbonyl)-N-(6-fluoro-2H-1,3-benzodioxol-5-yl)-1,3-thiazol-2-amine
InChI key:GGKQWFQQUMWVOB-UHFFFAOYSA-N

分子式:C18H19ClFN3O3S
分子量:411.88
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CC1CCCN(C1C)C(=O)c1nc(Nc2cc3OCOc3cc2F)sc1Cl
SMILES:CC1CCCN(C1C)C(=O)c1nc(Nc2cc3OCOc3cc2F)sc1Cl

GSK2332255B is a highly potent and selective TRPC3 and TRPC6 antagonist, exhibiting IC50 values of 5 nM and 4 nM for rat TRPC3 and rat TRPC6, respectively. Furthermore, GSK2332255B demonstrates exceptional selectivity, surpassing a ≥100-fold difference when compared to other calcium-permeable channels.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~