Name: Thalidomide-O-amido-PEG2-C2-NH2
Rating: 5 (10 reviews)

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HIT ID:HIT214322911
Cas No:1957235-74-3
常用名:Thalidomide-O-amido-PEG2-C2-NH2
别名:Thalidomide-O-amido-PEG2-C2-NH2, E3LigaseLigand-LinkerConjugates24, Cereblon Ligand-Linker Conjugates 10
别名:Thalidomide-O-amido-PEG2-C2-NH2, E3LigaseLigand-LinkerConjugates24, Cereblon Ligand-Linker Conjugates 10
IUPAC:N-{2-[2-(2-aminoethoxy)ethoxy]ethyl}-2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide
IUPAC:N-{2-[2-(2-aminoethoxy)ethoxy]ethyl}-2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide
InChI key:YNVIHPPEIRQPOL-UHFFFAOYSA-N

分子式:C21H26N4O8
分子量:462.459
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:NCCOCCOCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
SMILES:NCCOCCOCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12

Thalidomide-O-amido-PEG2-C2-NH2, which combines an E3 ligase ligand with a linker, serves as an immunomodulator for cancer treatment.

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