Name: PA Janelia Fluor 646, SE
Rating: 5 (10 reviews)

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HIT ID:HIT214323016
Cas No:2093120-32-0
常用名:PA Janelia Fluor 646, SE
别名:PA-JF646-NHS
IUPAC:2,5-dioxopyrrolidin-1-yl 6',12'-bis(azetidin-1-yl)-2-(-lambda5-diazynylidene)-9',9'-dimethyl-3-oxo-2,3-dihydro-9'-silaspiro[indene-1,2'-tricyclo[8.4.0.0^{3,8}]tetradecane]-1'(14'),3',5',7',10',12'-hexaene-6-carboxylate
IUPAC:2,5-dioxopyrrolidin-1-yl 6',12'-bis(azetidin-1-yl)-2-(-lambda5-diazynylidene)-9',9'-dimethyl-3-oxo-2,3-dihydro-9'-silaspiro[indene-1,2'-tricyclo[8.4.0.0^{3,8}]tetradecane]-1'(14'),3',5',7',10',12'-hexaene-6-carboxylate
InChI key:XVIATAHKOZWKHH-UHFFFAOYSA-N

分子式:C34H31N5O5Si
分子量:617.737
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:C[Si]1(C)c2cc(ccc2C2(C(=[N+]=[N-])C(=O)c3ccc(cc23)C(=O)ON2C(=O)CCC2=O)c2ccc(cc12)N1CCC1)N1CCC1
SMILES:C[Si]1(C)c2cc(ccc2C2(C(=[N+]=[N-])C(=O)c3ccc(cc23)C(=O)ON2C(=O)CCC2=O)c2ccc(cc12)N1CCC1)N1CCC1

PA Janelia Fluor 646, SE (PA-JF646-NHS), a photoactivatable fluorescent dye, is an NHS ester for coupling to primary amine groups. PA-JF646-NHS is non-fluorescent until activated at 365 nm. NHS ester can be converted to relevant substrate for use in self-labeling tag systems, e.g.HaloTag and SNAP-tag . PA-JF646-NHS is used for single molecule tracking and super resolution microscopy in live cells, specifically live cell sptPALM and fixed cell PALM. (λ Excitation/emission ~650/664 nm).

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