Name: Bromo-PEG4-NHS ester
Rating: 5 (10 reviews)

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结构编辑

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HIT ID:HIT214323123
Cas No:2148295-98-9
常用名:Bromo-PEG4-NHS ester
别名:Bromo-PEG4-NHS ester
IUPAC:2,5-dioxopyrrolidin-1-yl 1-bromo-3,6,9,12-tetraoxapentadecan-15-oate
IUPAC:2,5-dioxopyrrolidin-1-yl 1-bromo-3,6,9,12-tetraoxapentadecan-15-oate
InChI key:GIZQHAGVFHQMFN-UHFFFAOYSA-N

分子式:C15H24BrNO8
分子量:426.26
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:BrCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
SMILES:BrCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O

Bromo-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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