Name: CM121
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT214323172
Cas No:2204230-40-8
常用名:CM121
别名:CM121
IUPAC:1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-(4-methanesulfonylphenyl)-1H-pyrazole-4-carboxamide
IUPAC:1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-(4-methanesulfonylphenyl)-1H-pyrazole-4-carboxamide
InChI key:ZUWUBCCXJATTTE-UHFFFAOYSA-N

分子式:C24H17FN4O3S
分子量:460.48
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CS(=O)(=O)c1ccc(cc1)-c1nn(cc1C(=O)Nc1cccc(F)c1)-c1ccc(cc1)C#N
SMILES:CS(=O)(=O)c1ccc(cc1)-c1nn(cc1C(=O)Nc1cccc(F)c1)-c1ccc(cc1)C#N

CM121 is a reversible inhibitor of ALDH1A2 that acts specifically on the active site, exhibiting an IC50 of 0.54 μM and a Kd of 1.1 μM. It exerts its inhibitory effect through multiple hydrophobic interactions.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~