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  3. HIT214323199
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HIT214323199
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HIT214323199
  • HIT ID:HIT214323199
  • Cas No:2230472-55-4
  • 常用名:VGSC blocker-1
  • IUPAC:[4,4-bis(4-fluorophenyl)butyl][3-(piperidin-1-yl)propyl]amine
    IUPAC:[4,4-bis(4-fluorophenyl)butyl][3-(piperidin-1-yl)propyl]amine
  • InChI key:YHDCQGYFBMAZSX-UHFFFAOYSA-N
  • 分子式:C24H32F2N2
  • 分子量:386.531
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:Fc1ccc(cc1)C(CCCNCCCN1CCCCC1)c1ccc(F)cc1
    SMILES:Fc1ccc(cc1)C(CCCNCCCN1CCCCC1)c1ccc(F)cc1
  • VGSC blocker-1 is a powerful small molecule that serves as a blocker for the neonatal isoform of the VGSC subtype known as Nav1.5 (nNav1.5). It effectively blocks INa peak currents by 34.9% at a concentration of 1 μM, and demonstrates a 0.3% inhibition of cell invasion at the same concentration in the MDA-MB-231 human breast cancer cell line, without compromising cell viability.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    2-4周
    纯度
    -
    ¥ 10,600.00
    1

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