Name: DDO-2093
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT214323251
Cas No:2250024-74-7
常用名:DDO-2093
IUPAC:1-[3-(5-amino-2-chloro-4-fluoro-3-methylbenzamido)-4-(4-methylpiperazin-1-yl)phenyl]-N-[3-(morpholin-4-yl)propyl]-1H-1,2,3-triazole-4-carboxamide
IUPAC:1-[3-(5-amino-2-chloro-4-fluoro-3-methylbenzamido)-4-(4-methylpiperazin-1-yl)phenyl]-N-[3-(morpholin-4-yl)propyl]-1H-1,2,3-triazole-4-carboxamide
InChI key:MPTAUAHHFUFKAG-UHFFFAOYSA-N

分子式:C29H37ClFN9O3
分子量:614.12
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(N)c(F)c(C)c1Cl)-n1cc(nn1)C(=O)NCCCN1CCOCC1
SMILES:CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(N)c(F)c(C)c1Cl)-n1cc(nn1)C(=O)NCCCN1CCOCC1

DDO-2093, a powerful inhibitor of the MLL1-WDR5 protein-protein interaction (IC50 = 8.6 nM; Kd = 11.6 nM), exhibits prominent antitumor effects. Notably, DDO-2093 selectively hampers the catalytic activity of the MLL complex.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~