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  3. HIT214323260
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HIT214323260
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HIT214323260
  • HIT ID:HIT214323260
  • Cas No:2250313-14-3
  • 常用名:Influenza A virus-IN-1
  • IUPAC:ethyl 5-oxo-2-phenyl-1-[4-(trifluoromethyl)phenyl]-4-{[4-(trifluoromethyl)phenyl]amino}-2,5-dihydro-1H-pyrrole-3-carboxylate
    IUPAC:ethyl 5-oxo-2-phenyl-1-[4-(trifluoromethyl)phenyl]-4-{[4-(trifluoromethyl)phenyl]amino}-2,5-dihydro-1H-pyrrole-3-carboxylate
  • InChI key:IRTZGBURXBOHPW-UHFFFAOYSA-N
  • 分子式:C27H20F6N2O3
  • 分子量:534.458
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CCOC(=O)C1=C(Nc2ccc(cc2)C(F)(F)F)C(=O)N(C1c1ccccc1)c1ccc(cc1)C(F)(F)F |c:5|
    SMILES:CCOC(=O)C1=C(Nc2ccc(cc2)C(F)(F)F)C(=O)N(C1c1ccccc1)c1ccc(cc1)C(F)(F)F |c:5|
  • Influenza A virus-IN-1, a dihydropyrrolidones derivative, is a highly effective inhibitor of various subtypes of influenza A virus (IAV) with IC 50 values ranging from 3.11 μM to 7.13 μM. It effectively suppresses IAV replication and enhances the expression of key antiviral cytokines, such as IFN-β, and the antiviral protein MxA.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 10,600.00
    1

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