Name: Amine-PEG4-Desthiobiotin
Rating: 5 (10 reviews)

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HIT ID:HIT214323300
Cas No:2306109-91-9
常用名:Amine-PEG4-Desthiobiotin
别名:Amine-PEG4-Desthiobiotin
IUPAC:N-(14-amino-3,6,9,12-tetraoxatetradecan-1-yl)-6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanamide
IUPAC:N-(14-amino-3,6,9,12-tetraoxatetradecan-1-yl)-6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanamide
InChI key:DQZZCBCJTNOZDL-ZWKOTPCHSA-N

分子式:C20H40N4O6
分子量:432.562
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:C[C@@H]1NC(=O)N[C@@H]1CCCCCC(=O)NCCOCCOCCOCCOCCN
SMILES:C[C@@H]1NC(=O)N[C@@H]1CCCCCC(=O)NCCOCCOCCOCCOCCN

Amine-PEG4-Desthiobiotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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