Name: Desmorpholinyl Navitoclax-NH-Me
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT214323361
Cas No:2365172-82-1
常用名:Desmorpholinyl Navitoclax-NH-Me
别名:Desmorpholinyl Navitoclax-NH-Me, Desmorpholinyl ABT-263-NH-Me
别名:Desmorpholinyl Navitoclax-NH-Me, Desmorpholinyl ABT-263-NH-Me
IUPAC:4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-(4-{[(2R)-4-(methylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-trifluoromethanesulfonylbenzenesulfonyl)benzamide
IUPAC:4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-(4-{[(2R)-4-(methylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-trifluoromethanesulfonylbenzenesulfonyl)benzamide
InChI key:CNTHZPROCQHGOX-PGUFJCEWSA-N

分子式:C44H51ClF3N5O5S3
分子量:918.55
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CNCC[C@H](CSc1ccccc1)Nc1ccc(cc1S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(CC2=C(CCC(C)(C)C2)c2ccc(Cl)cc2)CC1 |t:47|
SMILES:CNCC[C@H](CSc1ccccc1)Nc1ccc(cc1S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(CC2=C(CCC(C)(C)C2)c2ccc(Cl)cc2)CC1 |t:47|

Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) 是一种 Bcl-xL 抑制剂，这是一种 PROTAC BCL-XL 降解剂,可与 CRBN 配体一起使用以合成 XZ739 [1] [2]。

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~