M-808 | CAS 2377335-74-3 | AnyMole

有库存

HIT214323383

sdf 文件

结构编辑

类似物检索

HIT214323383

HIT ID:HIT214323383
Cas No:2377335-74-3
常用名:M-808
IUPAC:methyl N-[(1S,2R)-2-[(1S)-2-(azetidin-1-yl)-1-(3-fluorophenyl)-1-[1-({1-[4-({1-[(2E)-4-(piperidin-1-yl)but-2-enoyl]azetidin-3-yl}sulfonyl)phenyl]azetidin-3-yl}methyl)piperidin-4-yl]ethyl]cyclopentyl]carbamate
IUPAC:methyl N-[(1S,2R)-2-[(1S)-2-(azetidin-1-yl)-1-(3-fluorophenyl)-1-[1-({1-[4-({1-[(2E)-4-(piperidin-1-yl)but-2-enoyl]azetidin-3-yl}sulfonyl)phenyl]azetidin-3-yl}methyl)piperidin-4-yl]ethyl]cyclopentyl]carbamate
InChI key:BTSUNSRQYLVGIS-ADTYUTHVSA-N

分子式:C45H63FN6O5S
分子量:819.09
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[H][C@@]1(CCC[C@@H]1NC(=O)OC)[C@@](CN1CCC1)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CN(C2)C(=O)\C=C\CN2CCCCC2)CC1)c1cccc(F)c1
SMILES:[H][C@@]1(CCC[C@@H]1NC(=O)OC)[C@@](CN1CCC1)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CN(C2)C(=O)\C=C\CN2CCCCC2)CC1)c1cccc(F)c1

M-808 is a potent and efficacious covalent inhibitor, targeting the interaction between Menin and MLL. It demonstrates a high binding affinity with an IC50 value of 2.6 nM.

市场产品/服务共显示1个结果

供应商
TargetMolSC
规格
货期
6-8周
纯度
-
¥ 69,000.00
1

寻找合适的化合物库

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

TargetMol | Target Loading

正在加载 ~