Name: Mal-PEG4-C2-NH2 TFA
Rating: 5 (10 reviews)

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HIT ID:HIT214323557
Cas No:2512227-13-1
常用名:Mal-PEG4-C2-NH2 TFA
别名:Mal-PEG4-C2-NH2 TFA
IUPAC:1-(14-amino-3,6,9,12-tetraoxatetradecan-1-yl)-2,5-dihydro-1H-pyrrole-2,5-dione; trifluoroacetic acid
IUPAC:1-(14-amino-3,6,9,12-tetraoxatetradecan-1-yl)-2,5-dihydro-1H-pyrrole-2,5-dione; trifluoroacetic acid
InChI key:VZGVXVADGJIXQP-UHFFFAOYSA-N

分子式:C16H25F3N2O8
分子量:430.377
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:OC(=O)C(F)(F)F.NCCOCCOCCOCCOCCN1C(=O)C=CC1=O |c:24|
SMILES:OC(=O)C(F)(F)F.NCCOCCOCCOCCOCCN1C(=O)C=CC1=O |c:24|

Mal-PEG4-C2-NH2 TFA is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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