Name: FP-Biotin
Rating: 5 (10 reviews)

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HIT ID:HIT214323608
Cas No:259270-28-5
常用名:FP-Biotin
别名:FP-生物素
IUPAC:ethyl {9-[(5-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}pentyl)carbamoyl]nonyl}phosphonofluoridate
IUPAC:ethyl {9-[(5-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}pentyl)carbamoyl]nonyl}phosphonofluoridate
InChI key:ZIFSFLGSUTZFCP-ZQCNBMBSSA-N

分子式:C27H50FN4O5PS
分子量:592.75
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[H][C@]12CS[C@@H](CCCCC(=O)NCCCCCNC(=O)CCCCCCCCCP(F)(=O)OCC)[C@@]1([H])NC(=O)N2
SMILES:[H][C@]12CS[C@@H](CCCCC(=O)NCCCCCNC(=O)CCCCCCCCCP(F)(=O)OCC)[C@@]1([H])NC(=O)N2

FP-biotin is a potent organophosphorus toxicant, ideal for identifying novel biomarkers of organophosphorus toxicant exposure. It measures FAAH, ABHD6, and MAG-lipase activity, specifically in plasma studies, due to the efficient purification of biotinylated peptides through binding to immobilized avidin beads.

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